SimEvolEnzCons: Simulation of Evolution of Enzyme Under Constraints

Simulate the evolution of enzyme concentrations under selection for increased flux in a metabolic pathway, with cellular constraints. Create graphics for the simulation results. Compute evolutionary equilibrium and Range of Neutral Variations of enzyme concentrations. This package is part of "Coton, C., Talbot, G., Le Louarn, M., Dillmann, C., de Vienne, D. (2021) <bioRxiv:10.1101/2021.05.04.442631>". Version 2.0.0 and more takes account of regulation groups, and is part of a second article "Coton, C., Dillmann, C., de Vienne, D. (in progress)".

Version: 2.0.0
Depends: R (≥ 3.1.0)
Imports: stats, rgl, ade4, graphics, grDevices, RColorBrewer, scatterplot3d
Published: 2021-10-28
Author: Charlotte Coton ORCID iD [aut, cre], Gregoire Talbot [aut], Maud Le Louarn [aut], Christine Dillmann ORCID iD [aut, ths], Dominique de Vienne ORCID iD [aut, ths]
Maintainer: Charlotte Coton <charlotte.coton at universite-paris-saclay.fr>
License: GPL (≥ 3)
NeedsCompilation: no
Materials: NEWS
CRAN checks: SimEvolEnzCons results

Documentation:

Reference manual: SimEvolEnzCons.pdf

Downloads:

Package source: SimEvolEnzCons_2.0.0.tar.gz
Windows binaries: r-devel: SimEvolEnzCons_2.0.0.zip, r-release: SimEvolEnzCons_2.0.0.zip, r-oldrel: SimEvolEnzCons_2.0.0.zip
macOS binaries: r-release (arm64): SimEvolEnzCons_2.0.0.tgz, r-release (x86_64): SimEvolEnzCons_2.0.0.tgz, r-oldrel: SimEvolEnzCons_2.0.0.tgz
Old sources: SimEvolEnzCons archive

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